View source for 7pl4


==Structure of Insulin receptor-related receptor's transmembrane domain==
<StructureSection load='7pl4' size='340' side='right'caption='[[7pl4]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7pl4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7PL4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7PL4 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7pl4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7pl4 OCA], [https://pdbe.org/7pl4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7pl4 RCSB], [https://www.ebi.ac.uk/pdbsum/7pl4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7pl4 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/INSRR_HUMAN INSRR_HUMAN] Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.<ref>PMID:21641549</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Bershatsky YV]]
[[Category: Bocharov EV]]
[[Category: Bocharova OV]]
[[Category: Nadezhdin KD]]