View source for 7pn0


==Crystal structure of the Phosphorybosylpyrophosphate synthetase II from Thermus thermophilus at R32 space group==
<StructureSection load='7pn0' size='340' side='right'caption='[[7pn0]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7pn0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=7awo 7awo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7PN0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7PN0 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7pn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7pn0 OCA], [https://pdbe.org/7pn0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7pn0 RCSB], [https://www.ebi.ac.uk/pdbsum/7pn0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7pn0 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q5SHU3_THET8 Q5SHU3_THET8] Involved in the biosynthesis of ribose 1,5-bisphosphate. Catalyzes the transfer of pyrophosphoryl group from ATP to ribose-5-phosphate to yield phosphoribosyl diphosphate (PRPP) and AMP.[HAMAP-Rule:MF_00583]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermus thermophilus]]
[[Category: Abramchik YA]]
[[Category: Esipov RS]]
[[Category: Kostromina MA]]
[[Category: Kuranova IP]]
[[Category: Timofeev VI]]