View source for 7pvt


==Crystal structure of the v-Src SH3 domain Q128R mutant in complex with the synthetic peptide VSL12==
<StructureSection load='7pvt' size='340' side='right'caption='[[7pvt]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7pvt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rous_sarcoma_virus_(strain_Schmidt-Ruppin_E) Rous sarcoma virus (strain Schmidt-Ruppin E)] and [https://en.wikipedia.org/wiki/Unidentified Unidentified]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7PVT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7PVT FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7pvt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7pvt OCA], [https://pdbe.org/7pvt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7pvt RCSB], [https://www.ebi.ac.uk/pdbsum/7pvt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7pvt ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SRC_RSVSE SRC_RSVSE] This phosphoprotein, required for both the initiation and the maintenance of neoplastic transformation, is a protein kinase that catalyzes the phosphorylation of tyrosine residues in vitro (By similarity).
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</StructureSection>
[[Category: Large Structures]]
[[Category: Unidentified]]
[[Category: Camara-Artigas A]]
[[Category: Salinas-Garcia MC]]