View source for 7qo2


==Peptide GAKSAA in complex with human cathepsin V C25A mutant==
<StructureSection load='7qo2' size='340' side='right'caption='[[7qo2]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7qo2]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7QO2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7QO2 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.77&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=TFA:TRIFLUOROACETIC+ACID'>TFA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7qo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7qo2 OCA], [https://pdbe.org/7qo2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7qo2 RCSB], [https://www.ebi.ac.uk/pdbsum/7qo2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7qo2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CATL2_HUMAN CATL2_HUMAN] Cysteine protease. May have an important role in corneal physiology.<ref>PMID:9727401</ref> <ref>PMID:10029531</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Demol H]]
[[Category: Gevaert K]]
[[Category: Horvat J]]
[[Category: Impens F]]
[[Category: Kosec G]]
[[Category: Loboda J]]
[[Category: Sosnowski P]]
[[Category: Turk B]]
[[Category: Turk D]]
[[Category: Tusar L]]
[[Category: Vidmar R]]
[[Category: Vizovisek M]]