View source for 7qri


==Regulatory domain dimer of tryptophan hydroxylase 2 in complex with L-Phe==
<StructureSection load='7qri' size='340' side='right'caption='[[7qri]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7qri]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7QRI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7QRI FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PHE:PHENYLALANINE'>PHE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7qri FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7qri OCA], [https://pdbe.org/7qri PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7qri RCSB], [https://www.ebi.ac.uk/pdbsum/7qri PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7qri ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/TPH2_HUMAN TPH2_HUMAN] Disease susceptibility is associated with variations affecting the gene represented in this entry.  Disease susceptibility is associated with variations affecting the gene represented in this entry. Naturally occurring variants of TPH2 with impaired enzyme activity could cause deficiency of serotonin production and result in an increased risk of developing behavioral disorders.
== Function ==
[https://www.uniprot.org/uniprot/TPH2_HUMAN TPH2_HUMAN] 

==See Also==
*[[Hydroxylases 3D structures|Hydroxylases 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Harris P]]
[[Category: Kragelund BB]]
[[Category: Peters GHJ]]
[[Category: Prestel A]]
[[Category: Vedel IM]]