View source for 7rw5


==Crystal structure of human methionine adenosyltransferase 2A (MAT2A) in complex with SAM and allosteric inhibitor Compound 1==
<StructureSection load='7rw5' size='340' side='right'caption='[[7rw5]], [[Resolution|resolution]] 2.48&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RW5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RW5 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.48&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7U2:(3R)-N-(cyclopropylmethyl)-1-[(2-fluorophenyl)methyl]-4-methyl-5H,7H-spiro[pyrano[4,3-d]pyrimidine-8,3-pyrrolidin]-2-amine'>7U2</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rw5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rw5 OCA], [https://pdbe.org/7rw5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rw5 RCSB], [https://www.ebi.ac.uk/pdbsum/7rw5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rw5 ProSAT]</span></td></tr>
</table>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Jin L]]
[[Category: Padyana AK]]