View source for 7sx3


==Human NALCN-FAM155A-UNC79-UNC80 channelosome with CaM bound, conformation 1/2==
<StructureSection load='7sx3' size='340' side='right'caption='[[7sx3]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7sx3]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SX3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SX3 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PEV:(1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL+STEARATE'>PEV</scene>, <scene name='pdbligand=PGV:(1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL+(11E)-OCTADEC-11-ENOATE'>PGV</scene>, <scene name='pdbligand=TYS:O-SULFO-L-TYROSINE'>TYS</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7sx3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7sx3 OCA], [https://pdbe.org/7sx3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7sx3 RCSB], [https://www.ebi.ac.uk/pdbsum/7sx3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7sx3 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NALF1_HUMAN NALF1_HUMAN] Auxillary component of the NALCN sodium channel complex, a channel that regulates the resting membrane potential and controls neuronal excitability.<ref>PMID:32494638</ref> 

==See Also==
*[[Calmodulin 3D structures|Calmodulin 3D structures]]
*[[Green Fluorescent Protein 3D structures|Green Fluorescent Protein 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Arthur CP]]
[[Category: Ben-Johny M]]
[[Category: Chakouri N]]
[[Category: Chang T]]
[[Category: Chua HC]]
[[Category: Ciferri C]]
[[Category: Kschonsak M]]
[[Category: Leitner A]]
[[Category: Noland CL]]
[[Category: Patel N]]
[[Category: Payandeh J]]
[[Category: Pless SA]]
[[Category: Schott K]]
[[Category: Tam C]]
[[Category: Weidling C]]