View source for 7tac


==Cryo-EM structure of the (TGA3)2-(NPR1)2-(TGA3)2 complex==
<StructureSection load='7tac' size='340' side='right'caption='[[7tac]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7tac]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TAC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TAC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.6&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tac FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tac OCA], [https://pdbe.org/7tac PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tac RCSB], [https://www.ebi.ac.uk/pdbsum/7tac PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tac ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TGA3_ARATH TGA3_ARATH] Transcriptional activator that binds specifically to the DNA sequence 5'-TGACG-3'. Recognizes ocs elements like the as-1 motif of the cauliflower mosaic virus 35S promoter. Binding to the as-1-like cis elements mediate auxin- and salicylic acid-inducible transcription. Required to induce the systemic acquired resistance (SAR) via the regulation of pathogenesis-related genes expression. Binding to the as-1 element of PR-1 promoter is salicylic acid-inducible and mediated by NPR1. Could also bind to the Hex-motif (5'-TGACGTGG-3') another cis-acting element found in plant histone promoters.<ref>PMID:12897257</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Bartesaghi A]]
[[Category: Dong X]]
[[Category: Wu Q]]
[[Category: Zhou P]]
[[Category: Zhou Y]]