View source for 7tq6


==Structure of SARS-CoV-2 3CL protease in complex with the cyclopropane based inhibitor 14c==
<StructureSection load='7tq6' size='340' side='right'caption='[[7tq6]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TQ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TQ6 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IT3:(1S,2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]-2-{[N-({[(1R,2R)-2-propylcyclopropyl]methoxy}carbonyl)-L-leucyl]amino}propane-1-sulfonic+acid'>IT3</scene>, <scene name='pdbligand=ITG:(1R,2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]-2-{[N-({[(1R,2R)-2-propylcyclopropyl]methoxy}carbonyl)-L-leucyl]amino}propane-1-sulfonic+acid'>ITG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tq6 OCA], [https://pdbe.org/7tq6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tq6 RCSB], [https://www.ebi.ac.uk/pdbsum/7tq6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tq6 ProSAT]</span></td></tr>
</table>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Battaile KP]]
[[Category: Chamandi SD]]
[[Category: Chang KO]]
[[Category: Groutas WC]]
[[Category: Kim Y]]
[[Category: Liu L]]
[[Category: Lovell S]]
[[Category: Madden TK]]
[[Category: Nguyen HN]]
[[Category: Picard HR]]
[[Category: Thruman HA]]