View source for 7tsw


==Crystal Structure Of Human NADH-Cytochrome B5 Reductase T117D Mutant==
<StructureSection load='7tsw' size='340' side='right'caption='[[7tsw]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7tsw]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TSW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TSW FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tsw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tsw OCA], [https://pdbe.org/7tsw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tsw RCSB], [https://www.ebi.ac.uk/pdbsum/7tsw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tsw ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/NB5R3_HUMAN NB5R3_HUMAN] Recessive hereditary methemoglobinemia type 2;Recessive hereditary methemoglobinemia type 1. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/NB5R3_HUMAN NB5R3_HUMAN] Desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction.

==See Also==
*[[NADH-cytochrome b5 reductase|NADH-cytochrome b5 reductase]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Thibodeau PH]]
[[Category: Zheng A]]