View source for 7tzl


==The DH dehydratase domain of AlnB==
<StructureSection load='7tzl' size='340' side='right'caption='[[7tzl]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7tzl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_griseofuscus Streptomyces griseofuscus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TZL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TZL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tzl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tzl OCA], [https://pdbe.org/7tzl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tzl RCSB], [https://www.ebi.ac.uk/pdbsum/7tzl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tzl ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A7H1Q9H8_9ACTN A0A7H1Q9H8_9ACTN] Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain.[ARBA:ARBA00023442]
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</StructureSection>
[[Category: Large Structures]]
[[Category: Streptomyces griseofuscus]]
[[Category: Blackson W]]
[[Category: Nannenga BL]]
[[Category: Swain K]]
[[Category: Wang B]]
[[Category: Zhao H]]