View source for 7ui3


==Apo-form of Human Tryptophan 2,3-Dioxygenase Induced by NADH Binding==
<StructureSection load='7ui3' size='340' side='right'caption='[[7ui3]], [[Resolution|resolution]] 3.18&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7ui3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7UI3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7UI3 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.18&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZIQ:(2~{S})-2-azanyl-3-(1~{H}-indol-3-yl)-2-methyl-propanoic+acid'>ZIQ</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ui3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ui3 OCA], [https://pdbe.org/7ui3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ui3 RCSB], [https://www.ebi.ac.uk/pdbsum/7ui3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ui3 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/T23O_HUMAN T23O_HUMAN] Incorporates oxygen into the indole moiety of tryptophan. Has a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin (By similarity).
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Geeraerts Z]]
[[Category: Yeh S-R]]