View source for 7ulu


==Human DDAH1 soaked with its inhibitor ClPyrAA==
<StructureSection load='7ulu' size='340' side='right'caption='[[7ulu]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7ulu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ULU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ULU FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NOU:(2~{S})-2-azanyl-4-(pyridin-2-ylamino)butanoic+acid'>NOU</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ulu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ulu OCA], [https://pdbe.org/7ulu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ulu RCSB], [https://www.ebi.ac.uk/pdbsum/7ulu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ulu ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DDAH1_HUMAN DDAH1_HUMAN] Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Butrin A]]
[[Category: Fast W]]
[[Category: Liu D]]
[[Category: Tuley A]]
[[Category: Zheng Y]]