View source for 7umb


==NanoBRET tracer Tram-bo bound to a KSR2-MEK1 complex==
<StructureSection load='7umb' size='340' side='right'caption='[[7umb]], [[Resolution|resolution]] 3.23&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7umb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7UMB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7UMB FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.231&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=U9F:{3-[(1M,2M)-2-{[(1S,2P)-1H,1H-[2,2-bipyrrol]-5-yl-kappaN~1~]methylidene}-2H-pyrrol-5-yl-kappaN]-N-(2-{2-[3-({(3M)-3-[(4aM)-3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl}amino)-3-oxopropoxy]ethoxy}ethyl)propanamidato}(difluorido)boron'>U9F</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7umb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7umb OCA], [https://pdbe.org/7umb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7umb RCSB], [https://www.ebi.ac.uk/pdbsum/7umb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7umb ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KSR2_HUMAN KSR2_HUMAN] 
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Dar AC]]
[[Category: Khan KM]]
[[Category: Marsiglia WM]]