View source for 7vm2


==GluK3 D759G mutant receptor complex with UBP310 and spermine==
<StructureSection load='7vm2' size='340' side='right'caption='[[7vm2]], [[Resolution|resolution]] 5.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7vm2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VM2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VM2 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 5.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vm2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vm2 OCA], [https://pdbe.org/7vm2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vm2 RCSB], [https://www.ebi.ac.uk/pdbsum/7vm2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vm2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GRIK3_RAT GRIK3_RAT] Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds domoate > kainate >> L-glutamate = quisqualate >> AMPA = NMDA.<ref>PMID:21907808</ref> 

==See Also==
*[[Glutamate receptor 3D structures|Glutamate receptor 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Assaiya A]]
[[Category: Kumar J]]