View source for 7vwo


==TA complex from Mycobacterium tuberculosis==
<StructureSection load='7vwo' size='340' side='right'caption='[[7vwo]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7vwo]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VWO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VWO FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vwo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vwo OCA], [https://pdbe.org/7vwo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vwo RCSB], [https://www.ebi.ac.uk/pdbsum/7vwo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vwo ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/VPC43_MYCTU VPC43_MYCTU] Toxic component of a type II toxin-antitoxin (TA) system. An RNase (By similarity). Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin VapB43.[HAMAP-Rule:MF_00265]<ref>PMID:20011113</ref> 

==See Also==
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Eun H-J]]
[[Category: Lee B-J]]
[[Category: Lee J-Y]]