View source for 7wrq


==Structure of Human IGF1/IGFBP3/ALS Ternary Complex==
<StructureSection load='7wrq' size='340' side='right'caption='[[7wrq]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7wrq]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WRQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WRQ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.6&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wrq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wrq OCA], [https://pdbe.org/7wrq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wrq RCSB], [https://www.ebi.ac.uk/pdbsum/7wrq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wrq ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/ALS_HUMAN ALS_HUMAN] Short stature due to primary acid-labile subunit deficiency. The disease is caused by variants affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/ALS_HUMAN ALS_HUMAN] Involved in protein-protein interactions that result in protein complexes, receptor-ligand binding or cell adhesion.

==See Also==
*[[Insulin-like growth factor|Insulin-like growth factor]]
*[[Insulin-like growth factor binding protein 3D structures|Insulin-like growth factor binding protein 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Fu Y]]
[[Category: Kim H]]
[[Category: Kim HM]]