View source for 7wzb


==lipopolysaccharide assembly protein LapB (open)==
<StructureSection load='7wzb' size='340' side='right'caption='[[7wzb]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7wzb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WZB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WZB FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wzb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wzb OCA], [https://pdbe.org/7wzb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wzb RCSB], [https://www.ebi.ac.uk/pdbsum/7wzb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wzb ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q7CQG6_SALTY Q7CQG6_SALTY] Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.[HAMAP-Rule:MF_00994]
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</StructureSection>
[[Category: Large Structures]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
[[Category: Deng Z]]
[[Category: Dong C]]
[[Category: Dong H]]
[[Category: Li H]]
[[Category: Liu X]]
[[Category: Yan L]]
[[Category: Zhang Z]]