View source for 7xeq


==NifS with D-cysteine==
<StructureSection load='7xeq' size='340' side='right'caption='[[7xeq]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7xeq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XEQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XEQ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9YX:(2~{S},4~{S})-2-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]-1,3-thiazolidine-4-carboxylic+acid'>9YX</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xeq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xeq OCA], [https://pdbe.org/7xeq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xeq RCSB], [https://www.ebi.ac.uk/pdbsum/7xeq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xeq ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ISCS_HELPY ISCS_HELPY] Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
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</StructureSection>
[[Category: Helicobacter pylori]]
[[Category: Large Structures]]
[[Category: Fujishiro T]]
[[Category: Nakamura R]]