View source for 7xlb


==Cryo-EM structure of human pannexin 2==
<StructureSection load='7xlb' size='340' side='right'caption='[[7xlb]], [[Resolution|resolution]] 3.44&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7xlb]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XLB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XLB FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.44&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xlb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xlb OCA], [https://pdbe.org/7xlb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xlb RCSB], [https://www.ebi.ac.uk/pdbsum/7xlb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xlb ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PANX2_HUMAN PANX2_HUMAN] Ion channel with a slight anion preference (PubMed:36973289). Also able to release ATP (PubMed:36869038). Plays a role in regulating neurogenesis and apoptosis in keratinocytes (By similarity).[UniProtKB:Q6IMP4]<ref>PMID:36869038</ref> <ref>PMID:36973289</ref> 

==See Also==
*[[Pannexin|Pannexin]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Daping W]]
[[Category: Hang Z]]
[[Category: Huawei Z]]