View source for 7xtl


==Crystal structure of the C-terminal domain of human N-acetylglucosaminyltransferase IVa==
<StructureSection load='7xtl' size='340' side='right'caption='[[7xtl]], [[Resolution|resolution]] 1.97&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7xtl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XTL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XTL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.972&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xtl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xtl OCA], [https://pdbe.org/7xtl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xtl RCSB], [https://www.ebi.ac.uk/pdbsum/7xtl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xtl ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MGT4A_HUMAN MGT4A_HUMAN] Glycosyltransferase that catalyze the transfer of GlcNAc from UDP-GlcNAc to the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans through a beta1-4 linkage and participates in the production of tri- and tetra-antennary N-linked sugar chains (PubMed:17006639). Involved in glucose transport by mediating SLC2A2/GLUT2 glycosylation, thereby controlling cell-surface expression of SLC2A2 in pancreatic beta cells (By similarity).[UniProtKB:Q812G0]<ref>PMID:17006639</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Miyazaki T]]
[[Category: Mori S]]
[[Category: Oka N]]