View source for 7xvk


==Modularity of Phytophthora effectors enables host mimicry of a principal phosphatase==
<StructureSection load='7xvk' size='340' side='right'caption='[[7xvk]], [[Resolution|resolution]] 2.29&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7xvk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana] and [https://en.wikipedia.org/wiki/Phytophthora_sojae Phytophthora sojae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XVK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XVK FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.29&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xvk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xvk OCA], [https://pdbe.org/7xvk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xvk RCSB], [https://www.ebi.ac.uk/pdbsum/7xvk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xvk ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/2AAB_ARATH 2AAB_ARATH] The A subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Involved during developmental process such as seedling and floral developments. Seems to act as a negative regulator of PP2A catalytic activity. Associates with the serine/threonine-protein phosphatase PP2A catalytic subunit C and regulatory subunit B' to positively regulates beta-oxidation of fatty acids and protoauxins in peroxisomes by dephosphorylating peroxisomal beta-oxidation-related proteins (PubMed:25489022).<ref>PMID:14973165</ref> <ref>PMID:25489022</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Phytophthora sojae]]
[[Category: Wang J]]
[[Category: Wang Y]]