View source for 7ya4


==Formate dehydrogenase from Novosphingobium sp. AP12 with NAD and Azide==
<StructureSection load='7ya4' size='340' side='right'caption='[[7ya4]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7ya4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Novosphingobium_sp._AP12 Novosphingobium sp. AP12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YA4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YA4 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ya4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ya4 OCA], [https://pdbe.org/7ya4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ya4 RCSB], [https://www.ebi.ac.uk/pdbsum/7ya4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ya4 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/J2HCX1_9SPHN J2HCX1_9SPHN] Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.[HAMAP-Rule:MF_03210]
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</StructureSection>
[[Category: Large Structures]]
[[Category: Novosphingobium sp. AP12]]
[[Category: Kim K-J]]
[[Category: Kim S]]