View source for 7yb4


==Solution structure of homeodomain of EXTRADENTICLE==
<StructureSection load='7yb4' size='340' side='right'caption='[[7yb4]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7yb4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YB4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YB4 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yb4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yb4 OCA], [https://pdbe.org/7yb4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yb4 RCSB], [https://www.ebi.ac.uk/pdbsum/7yb4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yb4 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/EXD_DROME EXD_DROME] Transcription factor which acts with the selector homeodomain proteins altering the regulation of downstream target genes such as wingless (wg), teashirt (tsh) and decapentaplegic (dpp), thus affecting segmental identity. Delimits the eye field and prevent inappropriate eye development. Required for proper localization of chordotonal organs within the peripheral nervous system.<ref>PMID:8104703</ref> <ref>PMID:8100142</ref> <ref>PMID:7914871</ref> <ref>PMID:9346235</ref> <ref>PMID:9463350</ref> <ref>PMID:9450936</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Drosophila melanogaster]]
[[Category: Large Structures]]
[[Category: Acharya B]]
[[Category: Basak AJ]]
[[Category: De S]]
[[Category: Lee W]]