View source for 7ypf


==Crystal structure of AsfvPCNA in space group of P1==
<StructureSection load='7ypf' size='340' side='right'caption='[[7ypf]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7ypf]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/African_swine_fever_virus African swine fever virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YPF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YPF FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ypf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ypf OCA], [https://pdbe.org/7ypf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ypf RCSB], [https://www.ebi.ac.uk/pdbsum/7ypf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ypf ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A0A1E3R5_ASF A0A0A1E3R5_ASF] Plays a role in the inhibition of host innate immune system by acting as a negatively regulator of type I interferon production. Mechanistically, interacts with and prevents host IRF3 nuclear localization to inhibit its transcriptional activity.[ARBA:ARBA00034465]

==See Also==
*[[Proliferating cell nuclear antigen 3D structures|Proliferating cell nuclear antigen 3D structures]]
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</StructureSection>
[[Category: African swine fever virus]]
[[Category: Large Structures]]
[[Category: Gan JH]]
[[Category: Shao ZW]]