View source for 7ywd


==Human GDAP1 core domain, trigonal crystal form==
<StructureSection load='7ywd' size='340' side='right'caption='[[7ywd]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7ywd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YWD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YWD FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ywd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ywd OCA], [https://pdbe.org/7ywd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ywd RCSB], [https://www.ebi.ac.uk/pdbsum/7ywd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ywd ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/GDAP1_HUMAN GDAP1_HUMAN] Charcot-Marie-Tooth disease type 2H;Autosomal recessive intermediate Charcot-Marie-Tooth disease type A;Autosomal dominant Charcot-Marie-Tooth disease type 2K;Autosomal recessive Charcot-Marie-Tooth disease with hoarseness;Charcot-Marie-Tooth disease type 4A. The disease is caused by variants affecting the gene represented in this entry.  The disease is caused by variants affecting the gene represented in this entry.  The disease is caused by variants affecting the gene represented in this entry.  The disease is caused by variants affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/GDAP1_HUMAN GDAP1_HUMAN] Regulates the mitochondrial network by promoting mitochondrial fission.<ref>PMID:16172208</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Kursula P]]
[[Category: Raasakka A]]