View source for 8a0z


==Crystal structure of Candida auris dihydrofolate reductase complexed with NADPH and pyrimethamine==
<StructureSection load='8a0z' size='340' side='right'caption='[[8a0z]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8a0z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_auris Candida auris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8A0Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8A0Z FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CP6:5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE'>CP6</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8a0z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8a0z OCA], [https://pdbe.org/8a0z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8a0z RCSB], [https://www.ebi.ac.uk/pdbsum/8a0z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8a0z ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A0L0P1H8_CANAR A0A0L0P1H8_CANAR] 
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Dias MVB]]
[[Category: Kirkman TK]]