View source for 8acu


==Structure of Bacillus subtilis Rel in complex with DarB==
<StructureSection load='8acu' size='340' side='right'caption='[[8acu]], [[Resolution|resolution]] 2.97&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8acu]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ACU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ACU FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.97&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8acu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8acu OCA], [https://pdbe.org/8acu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8acu RCSB], [https://www.ebi.ac.uk/pdbsum/8acu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8acu ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RELA_BACSU RELA_BACSU] In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp, it is probably the hydrolysis activity that is required for optimal growth (Probable).<ref>PMID:18067544</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Large Structures]]
[[Category: Garcia-Pino A]]