View source for 8amf


==Cryo-EM structure of the RecA postsynaptic filament from S. pneumoniae==
<StructureSection load='8amf' size='340' side='right'caption='[[8amf]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8amf]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_Lambda Escherichia virus Lambda] and [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8AMF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8AMF FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.8&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AGS:PHOSPHOTHIOPHOSPHORIC+ACID-ADENYLATE+ESTER'>AGS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8amf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8amf OCA], [https://pdbe.org/8amf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8amf RCSB], [https://www.ebi.ac.uk/pdbsum/8amf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8amf ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RECA_STRR6 RECA_STRR6] Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs (By similarity). It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity). Required for DNA transformation; protects transforming DNA from degradation, possibly in combination with DprA (PubMed:14617176, PubMed:17803906). Present at 15,000-30,000 monomers per competent cell (PubMed:14617176).[HAMAP-Rule:MF_00268]<ref>PMID:14617176</ref> <ref>PMID:17803906</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia virus Lambda]]
[[Category: Large Structures]]
[[Category: Streptococcus pneumoniae]]
[[Category: Fronzes R]]
[[Category: Hertzog M]]
[[Category: Perry TN]]
[[Category: Polard P]]