View source for 8arp


==Crystal structure of DEAD-box protein Dbp2 in complex with ADP==
<StructureSection load='8arp' size='340' side='right'caption='[[8arp]], [[Resolution|resolution]] 3.05&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8arp]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ARP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ARP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.05&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8arp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8arp OCA], [https://pdbe.org/8arp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8arp RCSB], [https://www.ebi.ac.uk/pdbsum/8arp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8arp ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DBP2_YEAST DBP2_YEAST] ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing (PubMed:11585918, PubMed:7883168). Associates directly with chromatin, correlating with transcriptional activity (PubMed:22679025). Required for assembly of mRNA-binding proteins YRA1, NAB2, and MEX67 onto poly(A)+ RNA (PubMed:23721653).<ref>PMID:11585918</ref> <ref>PMID:22679025</ref> <ref>PMID:23721653</ref> <ref>PMID:7883168</ref> 

==See Also==
*[[Helicase 3D structures|Helicase 3D structures]]
*[[Nuclear receptor coactivator|Nuclear receptor coactivator]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Rety S]]
[[Category: Song QX]]
[[Category: Xi XG]]