View source for 8ati


==Human CtBP2(31-364) in complex with RAI2 peptide(315-322)==
<StructureSection load='8ati' size='340' side='right'caption='[[8ati]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8ati]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ATI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ATI FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ati FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ati OCA], [https://pdbe.org/8ati PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ati RCSB], [https://www.ebi.ac.uk/pdbsum/8ati PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ati ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CTBP2_HUMAN CTBP2_HUMAN] Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity).  Isoform 2 probably acts as a scaffold for specialized synapses.
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Goradia N]]
[[Category: Mullapudi E]]
[[Category: Wilmanns M]]