View source for 8bhz


==The apo-crystal structure of a variant form of the 28-kDa Schistosoma bovis glutathione transferase in orthorhombic form==
<StructureSection load='8bhz' size='340' side='right'caption='[[8bhz]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8bhz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schistosoma_bovis Schistosoma bovis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BHZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BHZ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bhz OCA], [https://pdbe.org/8bhz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bhz RCSB], [https://www.ebi.ac.uk/pdbsum/8bhz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bhz ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GST28_SCHBO GST28_SCHBO] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.  GST isoenzymes appear to play a central role in the parasite detoxification system. Other functions are also suspected including a role in increasing the solubility of haematin in the parasite gut.

==See Also==
*[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Schistosoma bovis]]
[[Category: Achilonu IA]]
[[Category: Mfeka SM]]
[[Category: Onisuru O]]
[[Category: Pandian R]]
[[Category: Sayed Y]]