View source for 8bi8


==Structure of a cyclic beta-hairpin peptide derived from neuronal nitric oxide synthase==
<StructureSection load='8bi8' size='340' side='right'caption='[[8bi8]], [[Resolution|resolution]] 1.59&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8bi8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BI8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BI8 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.59&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DPR:D-PROLINE'>DPR</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bi8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bi8 OCA], [https://pdbe.org/8bi8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bi8 RCSB], [https://www.ebi.ac.uk/pdbsum/8bi8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bi8 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NOS1_HUMAN NOS1_HUMAN] Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Balboa JR]]
[[Category: Joerger AC]]
[[Category: Knapp S]]
[[Category: Ostergaard S]]
[[Category: Stromgaard K]]