View source for 8bik


==Crystal structure of human AMPK heterotrimer in complex with allosteric activator C455==
<StructureSection load='8bik' size='340' side='right'caption='[[8bik]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8bik]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BIK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BIK FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=QTN:(3~{R},3~{a}~{R},6~{R},6~{a}~{R})-6-[[6-chloranyl-5-[4-[4-[[dimethyl(oxidanyl)-$l^{4}-sulfanyl]amino]phenyl]phenyl]-3~{H}-imidazo[4,5-b]pyridin-2-yl]oxy]-2,3,3~{a},5,6,6~{a}-hexahydrofuro[3,2-b]furan-3-ol'>QTN</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=STU:STAUROSPORINE'>STU</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bik FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bik OCA], [https://pdbe.org/8bik PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bik RCSB], [https://www.ebi.ac.uk/pdbsum/8bik PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bik ProSAT]</span></td></tr>
</table>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Boland ML]]
[[Category: Hansen J]]
[[Category: Hemsley P]]
[[Category: Mather KM]]
[[Category: Read JA]]
[[Category: Rivers EL]]
[[Category: Robinson J]]
[[Category: Schimpl M]]
[[Category: Smith DM]]
[[Category: Srivastava A]]
[[Category: Trevaskis JL]]
[[Category: Wan PT]]