View source for 8bje


==A structure of the truncated LpMIP with bound inhibitor JK236.==
<StructureSection load='8bje' size='340' side='right'caption='[[8bje]], [[Resolution|resolution]] 1.49&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8bje]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Legionella_pneumophila Legionella pneumophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BJE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BJE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.49&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=WRL:(1~{S},5~{S},6~{R})-10-[3,5-bis(chloranyl)phenyl]sulfonyl-5-(hydroxymethyl)-3-[(1~{S})-1-pyridin-2-ylethyl]-3,10-diazabicyclo[4.3.1]decan-2-one'>WRL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bje FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bje OCA], [https://pdbe.org/8bje PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bje RCSB], [https://www.ebi.ac.uk/pdbsum/8bje PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bje ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MIP_LEGPH MIP_LEGPH] Essential virulence factor associated with macrophage infectivity. Exhibits PPIase activity.
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Legionella pneumophila]]
[[Category: Goretzki B]]
[[Category: Guskov A]]
[[Category: Hellmich UA]]
[[Category: Whittaker JJ]]