View source for 8bvz


==Spatial structure of amyloidogenic SEM1(49-67) peptide==
<StructureSection load='8bvz' size='340' side='right'caption='[[8bvz]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8bvz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BVZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BVZ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bvz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bvz OCA], [https://pdbe.org/8bvz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bvz RCSB], [https://www.ebi.ac.uk/pdbsum/8bvz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bvz ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SEMG1_HUMAN SEMG1_HUMAN] Predominant protein in semen. It participates in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. Fragments of semenogelin and/or fragments of the related proteins may contribute to the activation of progressive sperm movements as the gel-forming proteins are fragmented by KLK3/PSA.<ref>PMID:19889947</ref>   Alpha-inhibin-92 and alpha-inhibin-31, derived from the proteolytic degradation of semenogelin, inhibit the secretion of pituitary follicle-stimulating hormone.<ref>PMID:19889947</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Blokhin DS]]
[[Category: Osetrina DA]]
[[Category: Semenova EA]]
[[Category: Yulmetov AR]]