View source for 8bxt


==Structure of StayGold==
<StructureSection load='8bxt' size='340' side='right'caption='[[8bxt]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8bxt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cytaeis_uchidae Cytaeis uchidae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BXT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BXT FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CR2:{(4Z)-2-(AMINOMETHYL)-4-[(4-HYDROXYPHENYL)METHYLIDENE]-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>CR2</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bxt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bxt OCA], [https://pdbe.org/8bxt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bxt RCSB], [https://www.ebi.ac.uk/pdbsum/8bxt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bxt ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A8S0GSD4_9CNID A0A8S0GSD4_9CNID] 
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
StayGold is an exceptionally bright and stable fluorescent protein that is highly resistant to photobleaching. Despite favorable fluorescence properties, use of StayGold as a fluorescent tag is limited because it forms a natural dimer. Here we report the 1.6 A structure of StayGold and generate a derivative, mStayGold, that retains the brightness and photostability of the original protein while being fully monomeric.

A monomeric StayGold fluorescent protein.,Ivorra-Molla E, Akhuli D, McAndrew MBL, Scott W, Kumar L, Palani S, Mishima M, Crow A, Balasubramanian MK Nat Biotechnol. 2024 Sep;42(9):1368-1371. doi: 10.1038/s41587-023-02018-w. Epub , 2023 Dec 11. PMID:38081970<ref>PMID:38081970</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 8bxt" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Cytaeis uchidae]]
[[Category: Large Structures]]
[[Category: Akhuli D]]
[[Category: Crow A]]
[[Category: Ivorra-Molla E]]