View source for 8cgk


==Lincomycin and Avilamycin bound to the 50S subunit==
<StructureSection load='8cgk' size='340' side='right'caption='[[8cgk]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8cgk]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BW25113 Escherichia coli BW25113]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CGK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CGK FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 1.64&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1MG:1N-METHYLGUANOSINE-5-MONOPHOSPHATE'>1MG</scene>, <scene name='pdbligand=2MA:2-METHYLADENOSINE-5-MONOPHOSPHATE'>2MA</scene>, <scene name='pdbligand=2MG:2N-METHYLGUANOSINE-5-MONOPHOSPHATE'>2MG</scene>, <scene name='pdbligand=3QB:LINCOMYCIN'>3QB</scene>, <scene name='pdbligand=3TD:(1S)-1,4-ANHYDRO-1-(3-METHYL-2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL)-5-O-PHOSPHONO-D-RIBITOL'>3TD</scene>, <scene name='pdbligand=4D4:(2S,3R)-2-AZANYL-5-CARBAMIMIDAMIDO-3-OXIDANYL-PENTANOIC+ACID'>4D4</scene>, <scene name='pdbligand=5MC:5-METHYLCYTIDINE-5-MONOPHOSPHATE'>5MC</scene>, <scene name='pdbligand=5MU:5-METHYLURIDINE+5-MONOPHOSPHATE'>5MU</scene>, <scene name='pdbligand=6MZ:N6-METHYLADENOSINE-5-MONOPHOSPHATE'>6MZ</scene>, <scene name='pdbligand=6UQ:(2R,3S,4R,6S)-4-HYDROXY-6-{[(2R,3AR,4R,4R,5S,6S,6R,7AR)-4-HYDROXY-6-{[(2S,3R,4R,5S,6R)-3-HYDROXY-2-{[(2R,3S,4S,5S,6S)-4-HYDROXY-6-({(2R,3AS,3AR,6S,6R,7R,7R,7AR,7AR)-7-HYDROXY-7-[(1S)-1-HYDROXYETHYL]-6-METHYL-7-[(2-METHYLPROPANOYL)OXY]OCTAHYDRO-4H-2,4-SPIROBI[[1,3]DIOXOLO[4,5-C]PYRAN]-6-YL}OXY)-5-METHOXY-2-(METHOXYMETHYL)TETRAHYDRO-2H-PYRAN-3-YL]OXY}-5-METHOXY-6-METHYLTETRAHYDRO-2H-PYRAN-4-YL]OXY}-4,6,7A-TRIMETHYLOCTAHYDRO-4H-SPIRO[1,3-DIOXOLO[4,5-C]PYRAN-2,2-PYRAN]-5-YL]OXY}-2-METHYLTETRAHYDRO-2H-PYRAN-3-YL+3,5-DICHLORO-4-HYDROXY-2-METHOXY-6-METHYLBENZOATE+(NON-PREFERRED+NAME)'>6UQ</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=G7M:N7-METHYL-GUANOSINE-5-MONOPHOSPHATE'>G7M</scene>, <scene name='pdbligand=H2U:5,6-DIHYDROURIDINE-5-MONOPHOSPHATE'>H2U</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MEQ:N5-METHYLGLUTAMINE'>MEQ</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MS6:(2~{S})-2-azanyl-4-methylsulfanyl-butane-1-thiol'>MS6</scene>, <scene name='pdbligand=OMC:O2-METHYLYCYTIDINE-5-MONOPHOSPHATE'>OMC</scene>, <scene name='pdbligand=OMG:O2-METHYLGUANOSINE-5-MONOPHOSPHATE'>OMG</scene>, <scene name='pdbligand=OMU:O2-METHYLURIDINE+5-MONOPHOSPHATE'>OMU</scene>, <scene name='pdbligand=PSU:PSEUDOURIDINE-5-MONOPHOSPHATE'>PSU</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8cgk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8cgk OCA], [https://pdbe.org/8cgk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8cgk RCSB], [https://www.ebi.ac.uk/pdbsum/8cgk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8cgk ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RL33_ECOLI RL33_ECOLI] 
__TOC__
</StructureSection>
[[Category: Escherichia coli BW25113]]
[[Category: Large Structures]]
[[Category: Beckert B]]
[[Category: Crowe-McAuliffe C]]
[[Category: Paternoga H]]
[[Category: Wilson DN]]