View source for 8cnd


==Crystal structure of CREBBP-Y1482N histone acetyltransferase domain in complex with a bisubstrate inhibitor, Lys-CoA==
<StructureSection load='8cnd' size='340' side='right'caption='[[8cnd]], [[Resolution|resolution]] 2.97&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8cnd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CND OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CND FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.972&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=01K:[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl+(3R,20R)-20-carbamoyl-3-hydroxy-2,2-dimethyl-4,8,14,22-tetraoxo-12-thia-5,9,15,21-tetraazatricos-1-yl+dihydrogen+diphosphate'>01K</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8cnd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8cnd OCA], [https://pdbe.org/8cnd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8cnd RCSB], [https://www.ebi.ac.uk/pdbsum/8cnd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8cnd ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/F8VPR5_MOUSE F8VPR5_MOUSE] 
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Green M]]
[[Category: Haouz A]]
[[Category: Mechaly AE]]
[[Category: Rodrigues-Lima F]]
[[Category: Zhang W]]