View source for 8cpq


==Crystal structure of human protein disulfide isomerase PDIA6 domain b==
<StructureSection load='8cpq' size='340' side='right'caption='[[8cpq]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8cpq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CPQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CPQ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8cpq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8cpq OCA], [https://pdbe.org/8cpq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8cpq RCSB], [https://www.ebi.ac.uk/pdbsum/8cpq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8cpq ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PDIA6_HUMAN PDIA6_HUMAN] May function as a chaperone that inhibits aggregation of misfolded proteins. Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin.<ref>PMID:15466936</ref> <ref>PMID:12204115</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Hiller S]]
[[Category: Jakob RP]]
[[Category: Leder AL]]
[[Category: Maier T]]