View source for 8crh


==Crystal structure of Candida auris dihydrofolate reductase complexed with NADPH and cycloguanil==
<StructureSection load='8crh' size='340' side='right'caption='[[8crh]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8crh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_auris Candida auris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CRH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CRH FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=VIL:5-(4-chlorophenyl)-6,6-dimethyl-1,4-dihydro-1,3,5-triazine-2,4-diamine'>VIL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8crh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8crh OCA], [https://pdbe.org/8crh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8crh RCSB], [https://www.ebi.ac.uk/pdbsum/8crh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8crh ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A0L0P1H8_CANAR A0A0L0P1H8_CANAR] 
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Dias MVB]]
[[Category: Kirkman TJ]]