View source for 8ct7


==Catalytic Core Domain of HIV-1 Integrase (F185K) bound with BI-224436==
<StructureSection load='8ct7' size='340' side='right'caption='[[8ct7]], [[Resolution|resolution]] 2.13&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8ct7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CT7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CT7 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.13&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CAF:S-DIMETHYLARSINOYL-CYSTEINE'>CAF</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=L3D:(2~{S})-2-[2-methyl-4-(2-oxa-8-azatricyclo[7.3.1.0^{5,13}]trideca-1(13),5,7,9,11-pentaen-10-yl)quinolin-3-yl]-2-[(2-methylpropan-2-yl)oxy]ethanoic+acid'>L3D</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ct7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ct7 OCA], [https://pdbe.org/8ct7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ct7 RCSB], [https://www.ebi.ac.uk/pdbsum/8ct7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ct7 ProSAT]</span></td></tr>
</table>

==See Also==
*[[Retroviral integrase 3D structures|Retroviral integrase 3D structures]]
__TOC__
</StructureSection>
[[Category: Human immunodeficiency virus 1]]
[[Category: Large Structures]]
[[Category: Bushman FD]]
[[Category: Eilers G]]
[[Category: Gupta K]]
[[Category: Van Duyne GD]]