View source for 8d45


==Cryo-EM structure of human Kidney Betaine-Homocysteine Methyltransferase==
<StructureSection load='8d45' size='340' side='right'caption='[[8d45]], [[Resolution|resolution]] 2.62&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8d45]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8D45 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8D45 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.62&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8d45 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8d45 OCA], [https://pdbe.org/8d45 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8d45 RCSB], [https://www.ebi.ac.uk/pdbsum/8d45 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8d45 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BHMT1_HUMAN BHMT1_HUMAN] Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline.
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Lyu M]]
[[Category: Yu EW]]