View source for 8ddy


==Helical rods of far-red light-absorbing allophycocyanin in Synechococcus sp.==
<StructureSection load='8ddy' size='340' side='right'caption='[[8ddy]], [[Resolution|resolution]] 2.89&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8ddy]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Synechococcus_sp._63AY4M1 Synechococcus sp. 63AY4M1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DDY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DDY FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CYC:PHYCOCYANOBILIN'>CYC</scene>, <scene name='pdbligand=MEN:N-METHYL+ASPARAGINE'>MEN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ddy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ddy OCA], [https://pdbe.org/8ddy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ddy RCSB], [https://www.ebi.ac.uk/pdbsum/8ddy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ddy ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A2G8PAX6_9SYNE A0A2G8PAX6_9SYNE] 
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
To compete in certain low-light environments, some cyanobacteria express a paralog of the light-harvesting phycobiliprotein, allophycocyanin (AP), that strongly absorbs far-red light (FRL). Using cryo-electron microscopy and time-resolved absorption spectroscopy, we reveal the structure-function relationship of this FRL-absorbing AP complex (FRL-AP) that is expressed during acclimation to low light and that likely associates with chlorophyll a-containing photosystem I. FRL-AP assembles as helical nanotubes rather than typical toroids due to alterations of the domain geometry within each subunit. Spectroscopic characterization suggests that FRL-AP nanotubes are somewhat inefficient antenna; however, the enhanced ability to harvest FRL when visible light is severely attenuated represents a beneficial trade-off. The results expand the known diversity of light-harvesting proteins in nature and exemplify how biological plasticity is achieved by balancing resource accessibility with efficiency.

Helical allophycocyanin nanotubes absorb far-red light in a thermophilic cyanobacterium.,Gisriel CJ, Elias E, Shen G, Soulier NT, Flesher DA, Gunner MR, Brudvig GW, Croce R, Bryant DA Sci Adv. 2023 Mar 24;9(12):eadg0251. doi: 10.1126/sciadv.adg0251. Epub 2023 Mar , 24. PMID:36961897<ref>PMID:36961897</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 8ddy" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Synechococcus sp. 63AY4M1]]
[[Category: Brudvig GW]]
[[Category: Bryant DA]]
[[Category: Flesher DA]]
[[Category: Gisriel CJ]]
[[Category: Shen GS]]
[[Category: Soulier NT]]