View source for 8eao


==Cryo-EM structure of the in-situ gp1-gp4 complex from bacteriophage P22==
<StructureSection load='8eao' size='340' side='right'caption='[[8eao]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8eao]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_virus_P22 Salmonella virus P22]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8EAO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8EAO FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8eao FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8eao OCA], [https://pdbe.org/8eao PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8eao RCSB], [https://www.ebi.ac.uk/pdbsum/8eao PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8eao ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/EXLYS_BPP22 EXLYS_BPP22] Tail protein located at the vertex occupied by the portal ring. Together with gp10 and gp26, gp4 is required for stabilization of the condensed DNA within the capsid; perhaps by plugging the hole through which the DNA enters. Plays a role in ejection of the bacteriophage DNA into the host cell at the initiation of infection. Functions as an exolysin that catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycans.<ref>PMID:14763988</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Salmonella virus P22]]
[[Category: Liu J]]
[[Category: Molineux IJ]]
[[Category: Wang C]]