View source for 8eap


==Cryo-EM structure of the in-situ gp10-gp26 from bacteriophage P22==
<StructureSection load='8eap' size='340' side='right'caption='[[8eap]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8eap]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_virus_P22 Salmonella virus P22]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8EAP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8EAP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8eap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8eap OCA], [https://pdbe.org/8eap PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8eap RCSB], [https://www.ebi.ac.uk/pdbsum/8eap PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8eap ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NEEDL_BPP22 NEEDL_BPP22] Cell-perforating component and plug protein of the phage tail machine. Host cell membrane perforation allows viral DNA ejection. Together with gp4 and gp10, gp26 is required for stabilization of the condensed DNA within the capsid by plugging the hole through which the DNA enters.<ref>PMID:18059287</ref> <ref>PMID:20817910</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Salmonella virus P22]]
[[Category: Liu J]]
[[Category: Molineux IJ]]
[[Category: Wang C]]