View source for 8ebm


==Structure of KLHDC2 substrate binding domain bound to KLHDC2's C-degron mimic==
<StructureSection load='8ebm' size='340' side='right'caption='[[8ebm]], [[Resolution|resolution]] 1.58&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8ebm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8EBM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8EBM FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.58&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ebm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ebm OCA], [https://pdbe.org/8ebm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ebm RCSB], [https://www.ebi.ac.uk/pdbsum/8ebm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ebm ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KLDC2_HUMAN KLDC2_HUMAN] Represses CREB3-mediated transcription by interfering with CREB3-DNA binding.<ref>PMID:11384994</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Schulman BA]]
[[Category: Scott DC]]