View source for 8ecg


==Complex of HMG1 with pitavastatin==
<StructureSection load='8ecg' size='340' side='right'caption='[[8ecg]], [[Resolution|resolution]] 2.13&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8ecg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=7ulm 7ulm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ECG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ECG FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.13&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PV9:Pitavastatin'>PV9</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ecg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ecg OCA], [https://pdbe.org/8ecg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ecg RCSB], [https://www.ebi.ac.uk/pdbsum/8ecg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ecg ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HMDH1_ARATH HMDH1_ARATH] Catalyzes the synthesis of mevalonate, the specific precursor of all isoprenoid compounds present in plants.<ref>PMID:14871314</ref> <ref>PMID:17917299</ref> <ref>PMID:19041104</ref> <ref>PMID:19363204</ref> 

==See Also==
*[[HMG-CoA Reductase 3D structures|HMG-CoA Reductase 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Bond CS]]
[[Category: Haywood J]]