View source for 8fjc


==Structure of the catalytic domain of Streptococcus mutans GtfB complexed to acarbose in tetragonal space group P4322==
<StructureSection load='8fjc' size='340' side='right'caption='[[8fjc]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8fjc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8FJC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8FJC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AC1:6-METHYL-5-(4,5,6-TRIHYDROXY-3-HYDROXYMETHYL-CYCLOHEX-2-ENYLAMINO)-TETRAHYDRO-PYRAN-2,3,4-TRIOL'>AC1</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900007:alpha-acarbose'>PRD_900007</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8fjc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8fjc OCA], [https://pdbe.org/8fjc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8fjc RCSB], [https://www.ebi.ac.uk/pdbsum/8fjc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8fjc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GTFB_STRMU GTFB_STRMU] Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris.
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</StructureSection>
[[Category: Large Structures]]
[[Category: Streptococcus mutans]]
[[Category: Deivanayagam C]]
[[Category: Schormann N]]