View source for 8fy3


==Structure of NOT1:NOT10:NOT11 module of the human CCR4-NOT complex==
<StructureSection load='8fy3' size='340' side='right'caption='[[8fy3]], [[Resolution|resolution]] 2.88&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8fy3]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8FY3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8FY3 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.88&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8fy3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8fy3 OCA], [https://pdbe.org/8fy3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8fy3 RCSB], [https://www.ebi.ac.uk/pdbsum/8fy3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8fy3 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CNOT1_HUMAN CNOT1_HUMAN] Belongs to the CCR4-NOT complex that functions as general transcription regulation complex. Acts as a transcriptional repressor. Represses the ligand-dependent transcriptional activation by nuclear receptors.<ref>PMID:10637334</ref> <ref>PMID:16778766</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Deme JC]]
[[Category: Lea SM]]
[[Category: Pekovic F]]
[[Category: Raisch T]]
[[Category: Valkov E]]